While returning to Earth, the space shuttle explodes and the fragments bring an alien virus that recodes the human DNA. In Washington, the psychiatrist Carol Bennell observes the modification of the behavior of one of her clients first, then in her former husband and finally in the population in general. Together with her friend Dr. Ben Driscoll the researcher Dr. Stephen Galeano, they discover that the extraterrestrial epidemic affects human beings while sleeping and that her son Ollie, who had chickenpox when he was a baby, is immune to the disease and may save mankind from the outbreak.

In 1993, the Search for Extra Terrestrial Intelligence Project receives a transmission detailing an alien DNA structure, along with instructions on how to splice it with human DNA. The result is Sil, a sensual but deadly creature who can change from a beautiful woman to an armour-plated killing machine in the blink of an eye. Government agent Xavier Fitch assembles a team of scientists and mercenaries to locate and destroy Sil before she manages to find a mate and breed.

Shaun doesn't have a very good day, so he decides to turn his life around by getting his ex to take him back, but he times it for right in the middle of what may be a zombie apocalypse... But for him, it's an opportunity to show everyone he knows how useful he is by saving them all. All he has to do is survive... And get his ex back.

Hollywood star, Joe Scott, lives a life of narcissistic hedonism, observed by his laconic personal assistant, Ophelia. The death of his childhood best friend, Boots, takes our protagonist, and the movie, into an extended flashback to a sea-side town in 1970's Britain. Hollywood star Joe is now a teenage boy in a tentative relationship with a school-girl called Ruth. Furthhis mother's friend, Evelyn, is attempting to seduce him. Engulfed by guilt at the unintended, tragic consequences of his subterfuge, he leaves home. The movie then switches back to contemporary Hollywood. Joe confronts his fear and returns to England for a difficult meeting with Ruth, who had gone on to marry Boots and has been a left a poor widow.